As Tkobo said, lock the minister out from the bond market (bottom button on the econ minister main screen). After that, you can check your income and expenditures from the econ screen. compare "production" costs, and domestic sales. I have had production ministers decide to sell stuff domestically (and even exporting it) at a hefty loss just to drum up business, so if the production/domestic sales numbers are skewed, you might have to correct such a situation. Nothing will deplete your bank quicker than selling $20k manufactured goods for $18k.
Also, take a look at reducing the various social spending. Unless you have an election "next week", you can afford the DAR hit. Drop stuff like environmental spending and cultural subsidies. Infrastructure, Law enforcement, and Medical are the top three to spend money on, in that order. The others can be skimped on or even dropped to zero, at least temporarily. When the election draws near (a couple months away), you can increase social spending and lower domestic prices to raise DAR...until they re-elect you that is!
"My beloved people! I do not know how to properly thank you for granting me the honor of leading our great country for yet another four years! So... for lack of any better ideas to show my gratitude, I am hereby abolishing social security, welfare, and unemployment payments! If you are having trouble finding a job, please see your local army recruiter!"
In some rare fiscal emergencies, I have been known to completely shut down my research department as well. You probably don't need to be that drastic, but your ARE the Supreme Ruler
, play around and find out what works for you.